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Intestinal functionality: the dichotomy between nutrient and barrier function

The gut is adaptive and responds to ingredient matrix and bacterial environment. But these responses can alter endogenous maintenance as well as nutrient and energy digestibility. The gut response to pathogens depends on their amount, their virulence and of predisposing factors (e.g. cocci, mucin type, etc.). Gut immunological responses may vary nutrient “needs” with changes in tissue maintenance needs and nutrient use efficiencies.