[Music] so first of all good morning ladies and gentlemen and really welcome to Dubrovnik in Croatia this year for the second advance II Academy you remember that the first one was organized in Bangkok earlier in March this year prior to the AP PC and we focused at the time on rearing Birds and the hot conditions and now we are opening a new topic and we call that strengthening intestinal Frontier and underlining that it's key for performance and you might wonder why we use this term of intestinal frontier you know what we were facing in Europe in the recent years and months and it shows also that it's important to consider the intestinal wall not as a barrier but as a frontier we need to absorb nutrients that's a key point to performance to grow for the chief of the animals to produce egg milk and on we need to absorb so it's not a wall it's not about here it's really a frontier but you have to control like any frontier you have to accept or to refuse you know external things and so on so it's important so we say always frontier mother no barrier and we need to keep in mind that the intestinal wall is the last the last border before the blood so in fact after you enter into the body we sometimes forget that key points and we illustrate today along the whole program about nutrients so it's important to absorb nutrients but also to deal with an digestible part or even on key nutrition part and we will have illustration of with the example of phytate how that can challenge the intestinal mucosa for instance we talked a lot about gut frontier integrity with the tight junctions presentation we will also come see there and I think there will be a presentation to show the different components like the free radicals and redox balance as the intestinal level also we spent one of our chairman it's important to consider the immune system and to do not to forget that the intestine is a third immune system in the body of the animal and finally we talk about nutrition but we should never forget that we talk about an ecosystem a nutrition ecology it's clear it's so challenging our job as nutritionists is not giving bricks for the animal but it's also to deal with a lot of things from the animal from the microbiota from the interaction so I think it's very important to consider the gut as an ecosystem so I don't want to take too much time on the just introducing the day but I like this illustration from you remember you Eldora last year in the advance here we organized in Barcelona my feeling is today we are dealing with viability life is always a balance so when you consider that it means that between your gut frontier between the external and the internal you are always moving around so you have some viability so life is a balance some time we've got stresses challenges and then you have even more difficulties to cope with this variability and some time in fact the stress is too strong and then in fact you change the state so you go from a balanced state for an equilibrium to something which is this balanced which is moving apart and then when you are in this position it's much more difficult to come back to the previous state so to a balanced state back to normal is not so easy so our objective as nutritionists today is really to reinforce in fact the frontier helps the animal to be or robust you know to support challenges I think nutrition can improve robustness when we talk about nutrition and else we are not curing but we are helping to birds or sea animals to be more robust for any challenges so now I want to introduce our two chairman professor ben caspere's from germany band if you want to come on the stage and professor min gunshot from Australia I just remind you that's on the application advance application you have the full biography of this gentleman as well as all the speakers you are even if you don't remember the photo so you can put put that on your personal file but just to introduce very rapidly burnt you know is a vet working as a veterinary university of mimic and he published a lot of of papers is also an important guy on a Vienna mineralogy and I was interested looking at watching some of the previous presentation particularly in France or in European conference about the importance of the micro biota to develop the immune system at the gut level and the importance of the Cure team insisting in the whole immune response of the anymore so I think you will enjoy his presentation and it will also give this vet spirit I would say of the of our day today mingun you know very well everybody Minh gunshot has a nutritionist for many years he was one of the guy who influenced me most when I joined the company 22 years ago because my first at that time I was not working on enzyme I was working on energy metabolism but the first paper I read was Chuck and any son and that's back some years ago of a minyan and I always remember that influenced me because it was the first literature and good paper published on on enzyme so he publish a lot of papers he did also a very good connection with the industry with the poultry industry as a president of the CRC and now is more equivalent of the vice president of the University of New England so I know he has a lot of administrative part to deal with but he's still very interested by science and well I just remind you about the advances who if you have not yet downloaded the application just flash this flash code here or go in the corridor you can flush it and you will be able to ask questions to the speakers without raising their hands and be a shame about your English you know I don't I'm not so upset my own English or no problem but if you want to ask question you can type your question directly on the application you will be able also to use the application to keep your notes on the presentation you will be able also to ants were to speaker questions I asked some of the speakers to send questions and it would be interesting at the end of the day to look at you while you write on the answers to the questions and finally all the presentation the powerpoints and the videos and the voice and so on will be available on the channel dot online by end of next week at the latest and so that's what you will see on the on the application and now I will give the floor to our to external chairman performing and chant any professor ben caspere's thank you good morning ladies it's so great to be here in this beautiful town it's just gorgeous I haven't had time to go around yet but hopefully I will so welcome my name is Megan chalked Han from the University of New England in Australia I think a lot of you know me and I know you so it's so good to see you and your friends and we will meet up later at your morning tea so in the last advance here meeting we concluded that change is inevitable we need to embrace change so our industry is very very good at that embracing change and also going deep into the frontier of knowledge and these advance here's symposium is exactly about that it's we are going to look at the gut as a frontier so if you look at the gut well all nutrients are absorbed and digested in the gut it is the largest immune organ in the body it harvest all 'got microflora in fact the word excreta a chicken consists of 60% that originates from the organisms that are harbored in the gut so that's important also more than 20% of the body energy is expanded in the gut and a gut also contains more than 20 different hormones so when it comes to production nutrition immunology in a gut is an extremely important part we all know these so we are going to delve into more details of the gut looking at how the how the gut functions how are the organisms evolved and how the genes are expressed in the gut it's going to be absolutely exciting [Music]